Our Computational Biophysics Group at the University of California Riverside applies and develops computer simulations to characterize the mechanism of action of emerging proteins and nucleic acids that are transforming life sciences. We are interested in the dynamics and mechanism of novel gene-editing systems, such as CRISPR-Cas9 to enable facile manipulation of the genome.
We master molecular dynamics and multiscale modeling, quantum mechanical methods and cryo-electron microscopy (cryo-EM) processing techniques. Through these methods, we perform large-scale simulations of proteins and nucleic acids, with interest in bimolecular allostery, conformational change, and catalysis.
Our lab bridges the scales from quantum mechanical approaches to enhanced simulations and cryo-EM processing methods to push the boundaries of molecular simulations and tackle the future most exciting problems in biophysics.
We have a strong commitment toward increasing diversity and we welcome students with different backgrounds and origins. Visit our outreaching website to know more.